USING NATURAL IMMUNITY TO FIGHT CANCER
PETER J MURRAY, 2017, Departments of Infectious Diseases and Immunology
Macrophages are mainly involved in diverse immune molecular functions. The activation by different stimuli generates macrophages of different polarization with a spectrum of diverse purposes and functions.
The two known subgroups of macrophage polarization are the M1 and M2 polarization states. M1 macrophages are also called classically activated macrophages and feature pro-inflammatory effects, whereas M2 polarization leads to the alternatively activated anti-inflammatory state.
Our innovative approach has the potential to develop life-changing cellular therapies for cancer patients. We harness the natural power of macrophages by manipulating them to attack tumors. Our programmed anti-tumor macrophages can kill tumor cells and lead to long-term anti-tumor immunity, offering patients a promising new long-term strategy in the fight against cancer.
Macrophages are the highest instance of our immune system and are as powerful immune cells responsible for each immune response. These hyper-flexible cells can trigger more than 1000 different responses.
At Makrolife Biotech, we harness the endless possibilities of our immune system and immune cells through re-programmed repolarised macrophages that trigger a strong and targeted anti-tumor immune response.